01 - Pat tilapia fillets dry with paper towels. Combine chili powder, cumin, smoked paprika, garlic powder, salt, and black pepper in a small bowl. Rub seasoning mixture evenly over both sides of fillets. Drizzle with olive oil and lime juice, coating thoroughly.
02 - Heat a large nonstick skillet over medium-high heat. Place seasoned fillets in pan and cook for 3-4 minutes per side until golden brown and fish flakes easily with a fork. Remove from heat and let rest 2 minutes, then flake into bite-sized pieces.
03 - Combine shredded cabbage, carrots, and cilantro in a large bowl. Add lime juice and olive oil. Season with salt and pepper to taste. Toss until vegetables are evenly coated.
04 - Whisk together sour cream or Greek yogurt, lime juice, hot sauce if using, and salt in a small bowl until smooth and creamy. Adjust seasoning to taste.
05 - Heat tortillas in a dry skillet over medium heat for 30 seconds per side until warm and pliable. Alternatively, microwave stacked tortillas wrapped in damp paper towels for 30 seconds.
06 - Layer a generous portion of slaw onto each warm tortilla. Top with seasoned tilapia pieces. Drizzle with crema. Garnish with sliced avocado, fresh cilantro leaves, and a squeeze of fresh lime juice.
07 - Arrange tacos on a serving platter with extra lime wedges on the side. Serve immediately while tortillas are warm and fish is hot.